个人信息

　　王亚茹，女，副研究员。2006年毕业于中国农业科学院研究生院。主要开展饲用酶工程相关的研究。

　　研究方向与成果

　　长期从事高产饲用酶的菌种筛选与新颖基因资源的挖掘研究。获得国家科学技术进步奖二等奖和北京市科技进步一等奖各1项。

　　代表性论文和专利

　　Jiang X., Wang Y., Wang Y., Huang H., Bai Y., Su X., Zhang J., Yao B., Tu T.*, Luo H.* Exploiting the activity-stability trade-off of glucose oxidase from Aspergillus niger  using a simple approach to calculate thermostability of mutants. Food Chem. 2020, doi: 10.1016/j.foodchem.2020.128270.

　　Guo Y., Tu T., Zheng J., Ren Y., Wang Y., Bai Y., Su X., Wang Y., Yao B., Huang H., Luo H. A novel thermostable aspartic protease from Talaromyces leycettanus  and its specific autocatalytic activation through an intermediate transition state. Appl Microbiol Biotechnol. 2020, 104(11):4915-4926.

　　Sun X., Zhang X., Huang H., Wang Y., Tu T., Bai Y., Wang Y., Zhang J., Luo H., Yao B., Su X. Engineering the cbh1  promoter of Trichoderma reesei  for enhanced protein production by replacing the binding sites of a transcription repressor ACE1 to those of the activators. J Agric Food Chem. 2020, 68(5):1337-1346.

　　Chu Y., Hao Z., Wang K., Tu T., Huang H., Wang Y., Bai Y., Wang Y., Luo H., Yao B., Su X. The GH10 and GH48 dual-functional catalytic domains from a multimodular glycoside hydrolase synergize in hydrolyzing both cellulose and xylan. Biotechnol Biofuels. 2019, 12:279.

　　Yu X., Tu T., Luo H., Huang H., Su X., Wang Y., Wang Y., Zhang J., Bai Y., Yao B. Biochemical characterization and mutational analysis of a lactone hydrolase from Phialophora americana . J Agric Food Chem. 2020, 68(8):2570-2577.

　　Ren Y., Luo H., Huang H., Hakulinen N., Wang Y., Wang Y., Su X., Bai Y., Zhang J., Yao B., Wang G., Tu T. Improving the catalytic performance of Proteinase K from Parengyodontium album  for use in feather degradation. Int J Biol Macromol. 2020, 154:1586-1595.

　　Wang X., Bai Y., Huang H., Tu T., Wang Y., Wang Y., Luo H., Yao B., Su X. Degradation of aflatoxin B1 and zearalenone by bacterial and fungal laccases in presence of structurally defined chemicals and complex natural mediators. Toxins (Basel). 2019, 11(10):609.

　　Guo Y., Tu T., Zheng J., Bai Y., Huang H., Su X., Wang Y., Wang Y., Yao B., Luo H. Improvement of Bs APA aspartic protease thermostability via autocatalysis-resistant mutation. J Agric Food Chem. 2019, 67(37):10505-10512.

　　Guo Y., Tu T., Yuan P., Wang Y., Ren Y., Yao B., Luo H. High-level expression and characterization of a novel aspartic protease from Talaromyces leycettanus  JCM12802 and its potential application in juice clarification. Food Chem. 2019, 281:197-203.

　　Tu T., Wang Y., Huang H., Wang Y., Jiang X., Wang Z., Yao B., Luo H. Improving the thermostability and catalytic efficiency of glucose oxidase from Aspergillus niger  by molecular evolution. Food Chem. 2019, 281:163-170.

　　联系方式

　　E-mail: wangyaru@caas.cn